Protein name:
ATP-citrate synthase ;
Alternative:
Citrate cleavage enzyme ;ATP-citrate (pro-S-)-lyase ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MSAKAISEQT | GKELLYKYIC | TTSAIQNRFK | YARVTPDTDW | AHLLQDHPWL |
100:
LSQSLVVKPD | QLIKRRGKLG | LVGVNLSLDG | VKSWLKPRLG | HEATVGKAKG |
150:
FLKNFLIEPF | VPHSQAEEFY | VCIYATREGD | YVLFHHEGGV | DVGDVDTKAQ |
200:
KLLVGVDEKL | NAEDIKRHLL | VHAPEDKKEI | LASFISGLFN | FYEDLYFTYL |
250:
EINPLVVTKD | GVYILDLAAK | VDATADYICK | VKWGDIEFPP | PFGREAYPEE |
300:
AYIADLDAKS | GASLKLTLLN | PKGRIWTMVA | GGGASVVYSD | TICDLGGVNE |
350:
LANYGEYSGA | PSEQQTYDYA | KTILSLMTRE | KHPDGKILII | GGSIANFTNV |
400:
AATFKGIVRA | IRDYQGSLKE | HEVTIFVRRG | GPNYQEGLRV | MGEVGKTTGI |
450:
PIHVFGTETH | MTAIVGMAWA | PAIPNQPPTA | AHTANFLLNA | SGSTSTPAPS |
500:
RTASFSESRA | DEVAPAKKAK | PAMPQDSVPS | PRSLQGKSAT | LFSRHTKAIV |
550:
WGMQTRAVQG | MLDFDYVCSR | DEPSVAAMVY | PFTGDHKQKF | YWGHKEILIP |
600:
VFKNMADAMK | KHPEVDVLIN | FASLRSAYDS | TMETMNYAQI | RTIAIIAEGI |
650:
PEALTRKLIK | KADQKGVTII | GPATVGGIKP | GCFKIGNTGG | MLDNILASKL |
700:
YRPGSVAYVS | RSGGMSNELN | NIISRTTDGV | YEGVAIGGDR | YPGSTFMDHV |
750:
LRYQDTPGVK | MIVVLGEIGG | TEEYKICRGI | KEGRLTKPVV | CWCIGTCATM |
800:
FSSEVQFGHA | GACANQASET | AVAKNQALKE | AGVFVPRSFD | ELGEIIQSVY |
850:
EDLVAKGAIV | PAQEVPPPTV | PMDYSWAREL | GLIRKPASFM | TSICDERGQE |
900:
LIYAGMPITE | VFKEEMGIGG | VLGLLWFQRR | LPKYSCQFIE | MCLMVTADHG |
950:
PAVSGAHNTI | ICARAGKDLV | SSLTSGLLTI | GDRFGGALDA | AAKMFSKAFD |
1000:
SGIIPMEFVN | KMKKEGKLIM | GIGHRVKSIN | NPDMRVQILK | DFVKQHFPAT |
1050:
PLLDYALEVE | KITTSKKPNL | ILNVDGFIGV | AFVDMLRNCG | SFTREEADEY |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Rat ATP-citrate synthase
ELISA Kit for Rat ATP-citrate synthase
ELISA Kit for Rat ATP-citrate synthase
ELISA Kit for Rat ATP-citrate synthase
CLIA Kit for Rat ATP-citrate synthase
CLIA Kit for Rat ATP-citrate synthase
CLIA Kit for Rat ATP-citrate synthase
CLIA Kit for Rat ATP-citrate synthase
Polyclonal Antibody for Rat ATP-citrate synthase
Polyclonal Antibody for Rat ATP-citrate synthase
Polyclonal Antibody for Rat ATP-citrate synthase
Polyclonal Antibody for Rat ATP-citrate synthase
Monoclonal Antibody for Rat ATP-citrate synthase
Monoclonal Antibody for Rat ATP-citrate synthase
Monoclonal Antibody for Rat ATP-citrate synthase
Monoclonal Antibody for Rat ATP-citrate synthase
Protein for Rat ATP-citrate synthase
Protein for Rat ATP-citrate synthase
Protein for Rat ATP-citrate synthase
Protein for Rat ATP-citrate synthase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age."
Elshourbagy N.A.
,
Near J.C.
,
Kmetz P.J.
,
Sathe G.M.
,
Southan C.
,
Strickler J.E.
,
Gross M.
,
Young J.F.
,
Wells T.N.C.
,
Groot P.H.E.
J. Biol. Chem.265:1430-1435(1990)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Prostate .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 250-1100;ALTERNATIVE SPLICING;TISSUE SPECIFICITY
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 418-459;PHOSPHORYLATION AT THR-446 AND SER-450
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-454
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]